Types of Work Related Asthma

There are 3 types of work-related asthma:

  • Work-Aggravated:  when a person already has asthma but something at work makes the breathing symptoms worse.
  • New-Onset Asthma from a High Level Exposure to a Substance at Work:  when a person never had asthma before and was exposed to a spill or big leak of a chemical at work, and then developed asthma after that event.
  • New-Onset Asthma from Working with a Substance Known to Cause Asthma:  when a person may have worked with a substance at work, even for many years with no asthma symptoms and then develops asthma, months or years later.

For greater detail on the diagnosis and identification of the three types of work-related asthma, read the following scientific articles:

Substances at work that can cause asthma

There are more than 400 substances that have been reported in the medical literature that have been shown to cause work-related asthma. The list continues to grow. The main categories of substances that can cause asthma in the workplace include:

  • ANIMALS (dander, fur, etc.)
  • PLANTS and PLANT material
  • CHEMICALS

The following is a short list of examples of the types of jobs, industries, and the types of substances that can cause asthma. For an Exposure Code online look-up option for asthma-causing agents, refer to this web site: www.aoecdata.org/ExpCodeLookup.aspx.

Some of the More Common Workplace Exposures
Job or Type of IndustryType of Asthma-Causing Agent
    Animal or Insect Proteins
Laboratory animal workers
Veterinarians
dander and urine proteins
Food processingshellfish, egg proteins
Poultry farmerspoultry mites, droppings, feathers
Grain workersstorage mites, aspergillus, grass pollen
    Plant Proteins
Bakersflour dust
Food processingcoffee bean dust, tea, meat tenderizer
Farmerssoybean dust
Sawmill workers/carpenterswood dust (western red cedar, oak, mahogany, redwood, and others)
Electric solderingcolophony (pine resin)
Nursespsyllium, latex
    Chemicals
Platingnickel salts
Beauty shoppersulfates
Weldingstainless steel fumes, chromium salts
Hospital workersdisinfectants (formaldehyde, glutaraldehyde)
Plastics manufacturingTDI, HDI, Methylene diisocyanate, phthalic anhydride
Automobile paintingdimethyl ethanolamine diisocyanates

(Source: National Heart, Lung and Blood Institute. June 1992, Pub. No. 92-3091)

The National Institute for Occupational Safety and Health (NIOSH) has developed Alerts on several asthma causing agents. These Alerts provide important information on working with some of the more widely-used and dangerous asthma-causing agents. Click on the reports below to read the Alerts on:

Preventing Asthma in Animal Handlers
Preventing Asthma and Death from Diisocyanate Exposure
Preventing Allergic Reactions to Natural Rubber Latex in the Workplace
View the Federal OSHA’s website on metalworking fluids and asthma

Examples of Agents Capable of Causing Work-Related Asthma
Natural Products
vegetable gumsorris root
flax seedflour
castor beanpapain
soybeanmushroom dust and moldy composte
natural glueswood dusts
animal danders and other animal antigensnatural resins
coffee beananimal fat, oil and products
insect debrisfish meal and emulsions
detergent enzymestobacco dust
grain dusts and grain productspancreatic extracts
Synthetics
Inorganic Pharmaceuticals
platinum, complex saltspsyllium
nickel saltspenicillin
chromium saltsampicillin
sodium and potasiumspiramycin
persulphatesphenylglycine acid chloride
Organic Pharmaceuticals
sulphathiasolebromelin
diisocyanatesamprolium hydrochloride
toulenesulphone choloramides
diphenylmethanetetracycline
hexamethylene 
Miscellaneous Anhydrides
phthalicformaldehyde
tetrachlorophthallicpiperazine
trimelliticorganophosphorus insecticides
Miscellaneous Amines
pyrolysis products of polyvinyl chloride 
aminoethylalkylaryl polyether alcohol
ethanolaminetartrazine
dimethyl ethanolamineproducts of heated adhesives
ethylene diamine 
paraphenylenediamine 
diethylene triamine 
diethylene tetramine 

Based on materials reviewed and provided by the Michigan State University Occupational and Environmental Medicine Department, updated 2023