Tezepelumab - Medication Detail

Medication Type:  Long-term Control

Generic Names:  Tezepelumab

Brand Names:  Tezspire®

Description:  This medication is used as an add-on maintenance therapy for severe asthma in adults and pediatric patients 12 years of age and older.

It works over a few months to prevent the body’s reaction to allergens.

Delivery

Injection under the skin (subcutaneous)

Dosage

Adults and children 12 years and older.

  • 210 mg once every 4 weeks

Proper Use

A shot given into the fatty part of the skin on the thigh, lower abdomen, or upper arm every 4 weeks.

Precautions

  • Do NOT use this medication to treat an asthma attack
  • Allergic reactions to this medication have been reported
  • Your doctor will tell you how long you need to stay after each injection
  • Do not stop taking your other asthma medications or reduce their doses without your doctor’s approval
  • Pregnant women should talk with their doctor about the risks and benefits of using this medication

Common Interactions

This drug has no common interactions, but less common interactions exist.

This medication may enhance the adverse side effects of live vaccines.

Tell your doctor and pharmacist about all of your medications and health problems so they can look for any interactions.

Possible Side Effects

  • Bruising, redness, pain, or irritation where the shot is given
  • Headache, throat/mouth pain, and fever
  • Severe allergic reactions have been seen with this medication
  • Tell your doctor or get medical help if you notice any sign of an allergic reaction (rash, itching, wheezing, tightness in the chest or throat, trouble breathing, swelling of the mouth, face, lips tongue, or throat, feeling faint) or if you have a fever or joint pain

Proper Storage

  • This drug will be given to you in a hospital or doctor’s office
  • You will not store it at home