Medication Type
Long Term Control
Generic Names
Benralizumab
Brand Names
Fasenra®
Description
An injection to treat moderate to severe, persistent asthma not controlled with other long acting medications, such as inhaled corticosteroids. It works over a few months to prevent the body's reaction to allergens.
Delivery
By injection into the upper arm, thigh, or abdomen by patient, caregiver or healthcare professional, and is intended for use under the guidance of a healthcare provider.
Dosage
- Children aged 12 years and older and adults: 30 mg administered once every 4 weeks for the first 3 doses, and then once every 8 weeks thereafter
- Pre-filled pen available in 30 mg for home use
- Pre-filled syringe for use by health professionals only
Proper Use
- Before injection, remove the Fasenra pre-filled pen from the refrigerator and allow it to reach room temperature without removing the needle cap.
- Given as a shot in the fatty part of the skin. Patients may self-inject, or a caregiver may administer, after training has been provided by a healthcare provider on proper subcutaneous injection technique using the pre-filled pen. In adolescents 12 years of age and older, it is recommended that Fasenra be administered by or under the supervision of an adult. Patients and/or caregivers should read the Instructions for Use prior to injecting: pre-filled pen instructions.
Precautions
- Do NOT use this medication to treat an asthma attack
- Allergic reactions to this medication have been reported
- Your doctor will tell you how long you need to stay after each injection if receiving it in the doctor’s office
- Do not stop taking your other asthma medications or reduce their doses without your doctor's approval
- Pregnant women should talk with their doctor about the risks and benefits of using this medication
Common Interactions
This drug has no common interactions, but less common interactions exist.
Possible Side Effects
- Bruising, redness, pain, or irritation where the shot is given.
- Headache and fever
- Severe allergic reactions have been seen with this medication.
- Tell your doctor or get medical help if you notice any sign of an allergic reaction (rash, itching, wheezing, tightness in the chest or throat, trouble breathing, swelling of the mouth, face, lips tongue, or throat, feeling faint) or if you have a fever or joint pain.
Proper Storage
- Store by refrigerating at 36°F to 46°F (2°C to 8°C) in the original carton to protect from light.
- If necessary, pre-filled pens may be kept at room temperature up to 77°F (25°C) for a maximum of 14 days. After removal from the refrigerator, use within 14 days or throw away.
- Patients and/or caregivers should throw away any unused portion.
- Do NOT freeze. Do NOT heat. Do NOT shake.
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