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Medication Detail

image of medication detailed on this page

Medication Type

Long Term Control

Generic Names


Brand Names



An injection to treat moderate to severe, persistent asthma not controlled with other long acting medications, such as inhaled corticosteroids. It works over a few months to prevent the body’s reaction to allergens.


By injection into the upper arm, thigh, or abdomen by patient, caregiver or healthcare professional, and is intended for use under the guidance of a healthcare provider.


  • Adults (18+ years): Loading dose 600 mg, then 300 mg every two weeks
  • Children (6-17 years): Dosage is determined by weight
    • 60 kg (132 pounds): Loading dose 600 mg, then 300 mg every two weeks
    • 30-59 kg (66 to 130 pounds): Loading dose 400 mg, then 200 mg every two weeks
    • 15-29 kg (33 to 63 pounds): Loading dose 600 mg, then 300 mg every four weeks
  • Pre-filled pen (12+ years), available in 200 and 300 mg
  • Pre-filled syringe, available in 200 and 300 mg

Proper Use

  • Before injection, remove the Dupixent pre-filled pen or syringe from the refrigerator and allow it to reach room temperature without removing the needle cap.
  • Given as a shot in the fatty part of the skin. Patients may self-inject —or a caregiver may administer —after training has been provided by a healthcare provider on proper subcutaneous injection technique using the pre-filled syringe or pen. In adolescents 12 years of age and older, it is recommended that Dupixent be administered by or under the supervision of an adult. In children younger than 12 years of age, it should be given by a caregiver. Patients and/or caregivers should read the Instructions for Use prior to injecting:


  • Do NOT use this medication to treat an asthma attack
  • Allergic reactions to this medication have been reported
  • Do not stop taking your other asthma medications or reduce their doses without your doctor's approval
  • Pregnant women should talk with their doctor about the risks and benefits of using this medication

Common Interactions

This drug has no common interactions, but less common interactions exist.

Tell your doctor and pharmacist about all of your medications and health problems so they can look for any interactions.

Possible Side Effects

  • Bruising, redness, pain, or irritation where the shot is given.
  • Severe allergic reactions have been seen with this medication.
  • Tell your doctor or get medical help if you notice any sign of an allergic reaction (rash, itching, wheezing, tightness in the chest or throat, trouble breathing, swelling of the mouth, face, lips tongue, or throat, feeling faint) or if you have a fever or joint pain.

Proper Storage

If administering at home:
  • Dupixent is sterile and preservative-free. Patients and/or caregivers should throw away any unused portion
  • Store by refrigerating at 36°F to 46°F (2°C to 8°C) in the original carton to protect from light
  • If necessary, pre-filled pens or syringes may be kept at room temperature up to 77°F (25°C) for a maximum of 14 days. Do not store at higher than 77°F (25°C). After removal from the refrigerator, use within 14 days or throw away
  • The pen or syringe should not be exposed to heat or direct sunlight
  • Any unused medicinal product or waste material should be disposed of in accordance with local requirements
  • Do NOT freeze. Do NOT expose to heat. Do NOT shake

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